Benzene poisoning causes aplastic anemia into occupational disease killer

In recent years, the occurrence of aplastic anemia due to benzene poisoning continues to occur and threatens the lives of many workers. Experts said that in order to effectively protect the health rights of workers, preventive health measures must be taken to prevent benzene poisoning accidents.

“Although the country has repeatedly issued orders, the use of solvents, glues, and coatings containing high levels of benzene is still common in some factories. For example, if the concentration of benzene in the work environment is seriously exceeded, workers do not attach importance to protection, and long-term work involves high levels of benzene. In the environment, incidents of benzene poisoning causing workers with aplastic anaemia continue to occur in recent years. Our hospital has treated 30 to 40 patients in these two years, mostly young workers.” Liuhuaqiao Hospital, Guangzhou With the research center Dr. Yang Dezhao told reporters that benzene toxic aplastic anemia is still one of the occupational high incidence of diseases.

Aplastic Anemia Causes Complications

27-year-old Xiao Hu, who works in a jewellery processing factory, is responsible for the gluing of jewels. Therefore, she has been in close contact with benzene-containing glue for a long time. Due to lack of protective measures, Xiao Hu has been working in this environment for a long time. Causes chronic benzene poisoning. Because the mouth and nose often bleed, he thought he was starting to get angry and didn't pay attention. One day he suddenly fainted at work and lost consciousness, and was sent to the Guangdong Provincial Occupational Disease Prevention and Treatment Center to be diagnosed with aplastic anemia. For treatment, the hospital initially used immunosuppressive therapy, which caused a serious decline in the patient's immune function, resulting in secondary tuberculosis infection. The only hope was that bone marrow transplantation was performed at the time, but the patient's economy was not well-off and no match was found. Completely identical donor bone marrow.

“When he was transferred to the hospital, the situation was very critical. The young people in their 20s were so weak that they could not only walk, but they also lost their ability to work. They could only rely on drugs and blood transfusions to maintain their lives. They were treated in our hospital for almost a year. The condition gradually improved, and tuberculosis also cured.” Dr. Yang told reporters that not all patients are as lucky as Xiaohu, and there are still a large number of patients each year because they cannot find matching bone marrow, or are unable to afford high-level surgery. The cost of dying from aplastic anemia.

According to Dr. Yang, aplastic anemia is a disorder of hematopoietic function. The number of platelets, white blood cells, and hemoglobin in the patient's blood is much lower than normal. Can not supply normal physiological needs, in addition to the patient is extremely weak, the lack of platelets to the patient's mouth, nasal cavity often bleeding, if you eat something harder, even the gastrointestinal tract will also bleeding. The small number of white blood cells, the patient's resistance is very low, susceptible to complications such as tuberculosis.

Biological therapy for treatment of superior bone marrow transplantation

"Biological therapy has advantages over bone marrow transplantation." Dr. Yang pointed out that bone marrow transplantation is the preferred method for the treatment of aplastic anemia, but the current situation in China, the success rate of bone marrow matching is less than one-third, many patients Only rely on blood transfusion to survive, and the quality of life is severely reduced. This is because, on the one hand, there is a shortage of bone marrow inventories; on the other hand, the cost of bone marrow transplantation is also quite high. The average patient's cost is more than tens of thousands of yuan. It does not include blood transfusions and other expenses. It is difficult for ordinary people. Suffering, while bone marrow transplantation may be as rejection of other organ transplants, in order to reduce rejection, patients need to use immunosuppressive drugs, which is prone to other problems. As a result, many hospitals in recent years have adopted new biological therapies. This therapy does not have the problem of bone marrow matching, and the cost is relatively low. It is suitable for all patients of the same kind and has become a new hot spot in the treatment of hematological diseases at home and abroad.

According to statistics, the cure rate of biological atherosclerosis caused by benzene poisoning is as high as 100%, and the improvement of primary aplastic anemia is also very obvious.

Expert Weapon
Occupational benzene poisoning prevention

According to Dr. Deming Yang, benzene and other compounds enter the body from the respiratory tract in the form of vapors in the production environment. When inhaled in large quantities at high concentrations, acute benzene poisoning may occur. The anesthetic effect of the central nervous system is dominant, and the lighter ones experience excitement and euphoria. Unsteady gait, as well as headache, dizziness, nausea, vomiting, and mild confusion of consciousness, severe conscious confusion, coma or convulsions, severe breathing, cessation, and death.

At present, the common features of benzene poisoning in paint, manufacturing, leather, and box-packing workers are that production enterprises are mostly home-based workshops or small-scale processing enterprises. The technical level is low, the technology is backward, the operating environment is poor, and occupational protection facilities are lacking. And personal hygiene protection supplies, involving many people, serious consequences. In order to effectively protect the health rights and interests of workers, preventive health measures must be taken to prevent benzene poisoning accidents. Specific measures include: replacing benzene with low-toxic or non-toxic substances; reforming production processes and ventilating detoxification, such as the production process being closed, automated and programmed, and installing fully-exhausted local exhaust detoxification equipment. Health care measures include: Workers should wear anti-virus masks or masks, and regular health checks.

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